POMPE DISEASE: FROM PATHOPHYSIOLOGY TO THERAPY AND BACK AGAIN

Pompe disease: from pathophysiology to therapy and back again

Pompe disease is a lysosomal storage disorder in which acid alpha-glucosidase is deficient or absent.Deficiency of this lysosomal enzyme results in progressive expansion of glycogen-filled lysosomes in multiple tissues, with cardiac and Triangle Bra skeletal muscle being the most severely affected.The clinical spectrum ranges from fatal hypertrophi

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Understanding Compost-Bedded Pack Barn Systems in Regions with a Tropical Climate: A Review of the Current State of the Art

The main challenge in milk production has been to maintain a focus on efficient processes that enhance production outcomes while aligning with animal welfare and sustainability and being valued by society.As an alternative to improve cow welfare in production and provide better handling of the waste generated by the activity, the system called the

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Generation of Electrical Energy Obtained Through a Continuous Current Generator Coupled to the Pedal of an Ergometric Bicycle

ABSTRACT This study presents a system of conversion of mechanical energy produced by physical activity into electric energy obtained by a CC generator coupled to the pedal of an ergometric bicycle.It presents the sherpa jacket converter that will be used to adjust the voltage and power coming from the system, as well Lights as the details of the co

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PENGARUH PERUBAHAN DIVIDEND PAYOUT RATIO DAN DIVIDEND YIELD TERHADAP RETURN SAHAM (STUDI PADA PERUSAHAAN MANUFAKTUR DI BURSA EFEK INDONESIA)

This research aims to determine the effect of dividend payout ratio and dividend yield on stock price.Population taken consists of all manufacturing companies listed in the Indonesia Stock Exchange (IDX).From this, the sample was taken comprising 23 companies.This took a period from 2007 to 2011, using purposive sampling method with simple regressi

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